Coinfection by Hepatitis C Is Strongly Associated with Abnormal CD4/CD8 Ratio in HIV Patients under Stable ART in Salvador, Brazil

Table 4

Multivariate analysis of factors associated with different patterns of immune restoration.

Inadequate (plus partial) versus adequate immune restoration
Variable	Odds Ratio	95% CI
Lower mean CD4 nadir	1,002	1,001	1,004
Duration of virological suppression	1,000	1,000	1,000
Male gender	1,983	,971	4,048
Hepatitis C	18,748	5,309	66,210
Tuberculosis	2,046	,630	6,640

Adequate immune restoration: CD4 > 500 cells/mm³, and CD4/CD8 ratio > 1.0; Partial immune restoration: CD4 count > 500 cells/mm³, but CD4/CD8 ratio < 1.0; inadequate immune restoration: CD4 < 500 cells/mm³ and CD4/CD8 ratio < 1.0.