Review Article

In Vitro Selection of Cancer Cell-Specific Molecular Recognition Elements from Amino Acid Libraries

Table 3

Library screening methods for cell SELEX.

MethodAdvantagesDisadvantages

PanningHigh throughput, quick Less powerful separation, some undesired molecules remain after washes
Magnetic separation/MACSHigh throughputLimited space if using large cells (clogging), higher failure chance compared to panning with no advantages
FACSVery powerful separation ability with efficient tunabilityLower throughput, slower processing, expensive equipment