Balancing Innate Immunity and Inflammatory State via Modulation of Neutrophil Function: A Novel Strategy to Fight Sepsis

Figure 1

The development of sepsis has two phases, that is, activating and suppressing phase. The activation of the innate immune system can lead to a balanced response that can trigger the elimination of invading pathogens and the recovery of tissue but can also lead to an unbalanced response that can induce hyperinflammation or immune suppression.