The Expansion of CD25^highIL-10^highFoxP3^high B Regulatory Cells Is in Association with SLE Disease Activity

Figure 1

(a) A representative FACS analysis of purified B cells (expressing FoxP3) following CpG-ODN and CD40L activation. Of note is that B cells (upper left quadrant) do not express FoxP3. However, B cells coexpress significant amount of FoxP3 (upper right quadrant). (b) A representative FACS analysis of purified activated B cells, showing that CD3⁺ T cell contamination (gated T cells) is less than 0.5%.

(a)

(b)