The Expansion of CD25highIL-10highFoxP3high B Regulatory Cells Is in Association with SLE Disease Activity
(a) A representative FACS analysis of purified B cells (expressing FoxP3) following CpG-ODN and CD40L activation. Of note is that B cells (upper left quadrant) do not express FoxP3. However, B cells coexpress significant amount of FoxP3 (upper right quadrant). (b) A representative FACS analysis of purified activated B cells, showing that CD3+ T cell contamination (gated T cells) is less than 0.5%.