Journal of Immunology Research / 2015 / Article / Fig 4

Research Article

Mesenchymal Stem Cells Immunosuppressed IL-22 in Patients with Immune Thrombocytopenia via Soluble Cellular Factors

Figure 4

UC-MSCs immunosuppressed IL-22 by soluble cellular factors but not PGE2. (a) UC-MSCs inhibited CD4+T cells secreting IL-22 and the expression of IL-22 mRNA; (b) the immunoregulation of UC-MSCs on IL-22 was mediated by soluble cellular factors; (c) PGE2 did not involve in the immunoregulation of UC-MSCs on IL-22. Data represent one of the three independent experiments, each performed in triplicate. and .

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.