Age-Related Differences in Percentages of Regulatory and Effector T Lymphocytes and Their Subsets in Healthy Individuals and Characteristic STAT1/STAT5 Signalling Response in Helper T Lymphocytes

Figure 1

Th17 subset difference among populations. (a) The percentage of Th1Th17 lymphocytes in children was lower than those of adolescents or adults (b). Adult subjects had a higher percentage of total Th17 lymphocytes compared to both children and adolescents. (c) The increase in the percentage of Th17CD161+ lymphocytes in adults was significant compared to adolescents, and (d) the percentage of Th17CD161− lymphocytes in adults differed significantly from that in children. Each symbol in graphs (a) to (d) represents a single sample. The black lines in graphs (a) to (d) indicate the mean value with standard deviations. ; ; ; . (e) Gating strategies and staining patterns for identification of subpopulations Th1, Th2, Th1Th17, Th17CD161+, and Th17CD161−.

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