Osteoprotegerin Polymorphisms in a Mexican Population with Rheumatoid Arthritis and Generalized Osteoporosis: A Preliminary Report

Table 1

Genotyping strategies for TNFRSF11B polymorphism variants detection.

SNP	Primers	Band size (bp)	Restriction enzyme	Recognized sequence	Band size after digestion (bp)
C950T; rs2073617	5′-TGCGTCCGGATCTTGGCTGGATCGG-3′	548	Hinc II	GTY RAC	C 248 and 287; T 548
	5′-ACTTACCACGAGCGCGCAGCACAGCAA-3′
C209T; rs3134070	5′-CGAACCCTAGAGCAAAGTGC-3′	271	Taq I	T CGA	C 212, 31 and 28; T 212 and 59
	5′-TGTCTGATTGGCCCTAAAGC-3′
T245G; rs3134069	5′-CGAACCCTAGAGCAAAGTGC-3′	271	Hinf I	G ANTC	A 195, and 176; C 127, 76 and 69
	5′-TGTCTGATTGGCCCTAAAGC-3′

SNP: single nucleotide polymorphism and bp: base pair.