Vaccination with an Attenuated Ferritin Mutant Protects Mice against Virulent Mycobacterium tuberculosis

Table 2

Expression of selected immunity related genes in vaccinated animals.

Genes	BCG		ΔbfrB		Immunity type
	Mean^*	SE	Mean^*	SE
Il1a	1.28	0.59	1.23	0.57	Th1
Il1b	−1.09	0.10	−1.05	0.19	Th1
Il10	1.20	0.21	1.04	0.18	Th2, Th17
Il13	1.11	0.14	1.16	0.15	Th2, Th17
Il12a	−5.86	0.10	−2.21	0.28	Th1
Il12b	1.18	0.38	1.17	0.51	Th1, Th17
Il18ra	−1.04	0.18	−1.19	0.26	Th1
Ccl2	−1.09	0.11	1.13	0.07	Th17
Ccl7	−8.65	0.10	1.22	0.64	Th2, Th17
Ccl8	−4.12	0.17	5.34	4.82	Th2
Ccl12	1.81	1.04	4.78	3.64	Th17
Cxcl1	−1.72	0.38	7.13	6.25	Th17
Cxcl3	−1.27	0.37	4.92	3.40	Th2
Cxcl5	2.53	1.13	5.11	4.55	Th17
Cxcl11	−1.03	0.12	1.01	0.08	Th1
Tnfa	1.13	0.59	−2.51	0.29	Th1, Th17
Tgfb	−1.35	0.36	−1.27	0.41	Th2
Timp1	1.35	0.46	1.43	0.18	Th1, Th17
Il1r2	−1.48	0.22	−1.26	0.21	Th2
Nos2	−2.36	0.13	−1.03	0.39	Th1

Values shown are average from eight data points (duplicates of 4 animals per group).