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Journal of Immunology Research
Volume 2015 (2015), Article ID 473175, 10 pages
http://dx.doi.org/10.1155/2015/473175
Research Article

NKG2D Signaling Leads to NK Cell Mediated Lysis of Childhood AML

Department of Hematology and Oncology, University Children’s Hospital Tübingen, University of Tübingen, Hoppe-Seyler-Straße 1, 72076 Tübingen, Germany

Received 17 December 2014; Revised 9 June 2015; Accepted 16 June 2015

Academic Editor: David Kaplan

Copyright © 2015 Patrick Schlegel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The supplementary material provides additional analyses regarding the impact of HLA E on NK cell mediated cytolysis, comparative analyses of donor A and B taking into account blast HLA I genotype and NKG2DL high versus low expression on NK cytolysis.

  1. Supplementary Material