MBL2 Genotypes and Their Associations with MBL Levels and NICU Morbidity in a Cohort of Greek Neonates
Table 3
Overview of MBL2 genotypes and haplotypes in the subjects of the study.
NICU (neonatal intensive care)
Healthy ( 150)
Total ( 134)
Term ( 83)
Preterm ( 51)
(%)
(%)
*
(%)
(%)
*
MBL2 genotypes
YA/YA
HYA/HYA
13 (8.7)
10 (7.5)
0.732
6 (7.2)
4 (7.8)
0.903
LYA/LYA
7 (4.7)
4 (3.0)
0.480
1 (1.2)
3 (5.9)
0.136
HYA/LYA
31 (20.7)
28 (20.9)
0.969
16 (19.3)
12 (23.5)
0.636
YΑ/ΧΑ
LYA/LXA
9 (6.0)
10 (7.5)
0.645
4 (4.8)
6 (11.8)
0.171
HYA/LXA
16 (10.7)
11 (8.2)
0.521
9 (10.8)
2 (3.9)
0.188
ΧΑ/ΧΑ
LXA/LXA
6 (4.0)
9 (6.7)
0.333
7 (8.4)
2 (3.9)
0.341
YΑ/O
HYA/HYD
4 (2.7)
2 (1.5)
0.501
2 (2.4)
0 (0)
0.270
HYA/LYB
26 (17.3)
20 (14.9)
0.640
15 (18.1)
5 (9.8)
0.257
HYA/LYC
0 (0)
1 (0.7)
0.291
1 (1.2)
0 (0)
0.434
LYA/HYD
4 (2.7)
6 (4.5)
0.425
3 (3.6)
3 (5.9)
0.557
LYA/LYB
8 (5.3)
4 (3.0)
0.346
3 (3.6)
1 (2.0)
0.595
XA/O
LXA/LYB
9 (6.0)
14 (10.4)
0.206
9 (10.8)
5 (9.8)
0.863
LXA/HYD
7 (4.7)
2 (1.5)
0.139
1 (1.2)
1 (2.0)
0.730
LXA/LYC
0 (0)
1 (0.7)
0.291
1 (1.2)
0 (0)
0.434
O/O
LYB/LYB
5 (3.3)
7 (5.2)
0.449
4 (4.8)
3 (5.9)
0.799
LYB/HYD
5 (3.3)
3 (2.2)
0.588
1 (1.2)
2 (3.9)
0.314
HYD/HYD
0 (0)
2 (1.5)
0.136
0 (0)
2 (3.9)
0.075
MBL2 haplotypes
HYA
103 (34.3)
82 (30.6)
0.498
55 (33.1)
27 (26.5)
0.399
LYA
66 (22.0)
56 (20.9)
0.797
28 (18.9)
28 (27.5)
0.097
LXA
53 (17.7)
56 (20.9)
0.422
38 (22.9)
18 (17.6)
0.404
LYB
58 (19.3)
55 (20.5)
0.772
36 (21.7)
19 (18.6)
0.624
HYD
20 (6.7)
17 (6.3)
0.884
7 (4.2)
10 (9.8)
0.089
LYC
0
2 (0.7)
0.135
2 (1.2)
0 (0)
0.269
Statistical significance (chi-square test) refers to comparison of MBL2 genotypes between NICU and healthy neonates and to comparison of MBL2 genotypes between term and preterm neonates of NICU.