Low Baseline Interleukin-17A Levels Are Associated with Better Treatment Response at 12 Weeks to Tocilizumab Therapy in Rheumatoid Arthritis Patients

Table 2

Comparison of baseline serum cytokine levels in the IL-17A low group and the IL-17A high group.

	IL-17A low ( = 21)	IL-17A high ( = 23)	value
IL-17A levels	0.01 ± 0.00	11.69 ± 4.43	<0.001
TNF-α levels	6.38 ± 1.23	33.84 ± 11.00	0.001
IL-6 levels	8.46 ± 1.14	8.77 ± 1.14	0.879
sIL-6R levels	162.94 ± 7.68	170.37 ± 7.09	0.672
IL-21 levels	4.34 ± 1.48	140.05 ± 50.97	0.003
IL-23 levels	1.23 ± 0.54	15.11 ± 6.45	0.002

Data are presented as mean (±SEM) for continuous variables. TNF-α = tumor necrosis factor-alpha; IL = interleukin; sIL-6R = soluble interleukin 6 receptor.