CD69 Is the Crucial Regulator of Intestinal Inflammation: A New Target Molecule for IBD Treatment?

Figure 1

The structure of CD69 molecule. CD69 is membrane-bound protein, a homodimer of two (28 and 32 kDa) differentially glycosylated subunits. Each subunit consists of extracellular C-type lectin domain (CTLD) connected by the short neck region with the single spanning transmembrane domain and short cytoplasmatic tail. Subunits are connected with the disulfide bridge in the extracellular neck region.