SP140L, an Evolutionarily Recent Member of the SP100 Family, Is an Autoantigen in Primary Biliary Cirrhosis

Figure 4

Nuclear localization of the SP140L, SP140, SP110, and SP100A proteins in HeLa cells. SP140L (a–c) and SP140 (d–f) have a highly similar localization pattern in HeLa cell nuclei, which is distinctly different from either SP110 (g–i) or SP100A (j–l). Monoclonal anti-Myc antibody was used to detect SP140L and monoclonal anti-FLAG antibody was used to detect SP140, SP110, and SP100A. Scale bar: 5 μm.

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