Applying the Concept of Peptide Uniqueness to Anti-Polio Vaccination

Table 1

Pentapeptides unique to PV type 1, strain Mahoney, and absent in the human proteome.

Pos^a	Sequence^b,c	Pos^a	Sequence^b,c	Pos^a	Sequence^b,c	Pos^a	Sequence^b,c	Pos^a	Sequence^b,c	Pos^a	Sequence^b,c
11	GAHEN	393	MIPLN	746	PAKWD	969	YYPAR	1399	CHQPA	1750	EIQWM
29	TINYY	403	KNTMD	748	KWDDY	974	YQSHI	1403	ANFKR	1751	IQWMR
72	NIEAC	404	NTMDM	749	WDDYT	996	CHHGV	1413	CGKAI	1752	QWMRP
73	IEACG	408	MYRVQ	752	YTWQT	1014	FADIR	1418	QLMDK	1762	YPIIN
104	YGRWP	414	NDNPH	763	FYTYG	1021	YAYEE	1437	IVNER	1810	YVGNK
106	RWPEY	436	LSHTM	783	AYSHF	1084	ITRNY	1458	PIQYK	1840	TEQMC
107	WPEYL	446	NYYTH	784	YSHFY	1105	VSPWQ	1475	ECIND	1849	MYGTD
130	CRFYT	447	YYTHW	785	SHFYD	1136	TEACN	1489	VRNYC	1933	VAMRM
145	RGWWW	448	YTHWA	835	KIRVY	1139	CNAAK	1490	RNYCE	1935	MRMAF
146	GWWWK	449	THWAG	841	KPKHI	1188	STIHQ	1496	KGWIV	1946	FHKNP
148	WWKLP	464	SMMAT	847	VWCPR	1190	IHQSC	1497	GWIVN	1947	HKNPG
149	WKLPD	465	MMATG	857	AYYGP	1204	FNNVR	1498	WIVNI	1966	WSKIP
163	QNMYY	494	HVIWD	863	VDYKD	1205	NNVRW	1513	NRAMT	1979	AFDYT
164	NMYYH	495	VIWDI	880	TYGFG	1209	WLSIQ	1532	VYVMY	1983	TGYDA
165	MYYHY	497	WDIGL	881	YGFGH	1231	LEHTI	1534	VMYKL	1993	WFEAL
179	VQCNA	507	MVVPW	883	FGHQN	1291	FDGYK	1536	YKLFA	2028	YCVKG
199	MCLAG	510	PWISN	884	GHQNK	1311	GADMK	1588	GEFTM	2070	KMIAY
242	RFCPV	518	RQTTN	894	GYKIC	1314	MKLFC	1592	MLGIH	2073	AYGDD
244	CPVDY	534	FYQTR	895	YKICN	1326	FIPPM	1594	GIHDN	2115	TWENV
271	TNNCA	556	SACND	897	ICNYH	1340	FTSNY	1595	IHDNV	2131	KYPFL
292	KHNNW	557	ACNDF	912	VSTMW	1341	TSNYV	1596	HDNVA	2148	SIRWT
293	HNNWG	558	CNDFS	914	TMWDR	1368	RFAFD	1660	TETND	2158	TQDHV
295	NWGIA	568	DTTHI	934	ARCNC	1369	FAFDM	1677	MFVPV	2168	LAWHN
323	PMCC	569	TTHIG	942	VYYCE	1371	FDMDI	1699	RTLMY	2201	LYRRW
324	PMCCE	588	MIDNT	948	RRKYY	1388	DMTMA	1700	TLMYN
326	CCEFN	665	CVSII	959	PTFQY	1389	MTMAT	1701	LMYNF
327	CEFNG	708	RFDME	961	FQYME	1394	EMCKN	1702	MYNFP
391	DTMIP	735	QIMYV	962	QYMEA	1398	NCHQP	1742	SYFTQ

aa position along the human PV type 1, strain Mahoney, primary sequence.
^baa sequences given in one-letter code.
^cConsecutively overlapping pentapeptides forming 7- and 8-mer stretches unique to PV are given in bold.