New Insights into the Function of the Immunoproteasome in Immune and Nonimmune Cells

Figure 2

The immunoproteasome as a potential therapeutic target. The immunoproteasome plays an important role in immune responses, including processing viral proteins for antigen presentation, T cell differentiation, and macrophage activation. Recent studies have identified that the immunoproteasome is present in nonimmune cells, where it regulates cell differentiation and function.