Journal of Immunology Research / 2015 / Article / Fig 1

Review Article

TRAIL Modulates the Immune System and Protects against the Development of Diabetes

Figure 1

TRAIL-receptor mediated signalling pathways. By binding its receptor TRAIL initiates cell death (apoptosis) via either intrinsic (mitochondria) or extrinsic pathway and/or induces the activation of survival genes resulting in cell proliferation/migration and inhibition of apoptosis.