Review Article

Current Mathematical Models for Analyzing Anti-Malarial Antibody Data with an Eye to Malaria Elimination and Eradication

Table 3

Bayesian analysis of P. falciparum seropositivity data from Jacearecanga where RCMred, , and RCMbehavior denote the reversible catalytic models assuming an abrupt reduction in SCR only, an abrupt reduction together with migration effects, and a change in SCR due to a behavioral factor dependent on a given age cut-off.

Model Parameter Posterior estimates
Mean Median 95% credible interval

RCMred Past SCR 0.4360.3860.099–0.948
Current SCR 0.0190.0190.009–0.033
Time elapsed since reduction 27.628.022.0–33.0
Past SCR 0.2920.1920.052–0.916
Current SCR 0.0380.0370.013–0.067
Time elapsed since reduction 24.526.04.0–39.0
RCMbehavior Baseline SCR 0.0510.0460.019–0.106
Risk SCR 0.6540.6930.153–0.988
Age cut-off 28.929.026.0–33.0

Credible interval based on 2.5% and 97.5% quantiles of the respective posterior distribution.