IFI16 Expression Is Related to Selected Transcription Factors during B-Cell Differentiation

Figure 1

IFI16 mRNA expression in normal B-cell subsets. IFI16 mRNA expression evaluated by GEP and presented in box plot (a) and interaction bar plot (b). Naïve and memory B-cells showed a significantly higher IFI16 mRNA level with respect to GC B-cells (naïve versus GC ; memory versus GC ; Mann-Whitney test) and PCs (naïve versus plasma cells ; memory versus PCs ; Mann-Whitney test) but no differences were noted between naïve and memory B-cell subsets (; Mann-Whitney test). GC cells showed a significant increase with respect to plasma cells (; Mann-Whitney test).

(a)

(b)