Uptake of CCR7 by KIR2DS4+ NK Cells Is Induced upon Recognition of Certain HLA-C Alleles
Comparison between KIR2DS4+ and KIR2DS4− NK cell clones in the killing of transfected 221 cell lines. (a, b) The cytolytic activity of KIR2DS4− NKG2A+ and KIR2DS4+ NKG2A+ NK cell clones (derived from a B haplotype donor) was analyzed against untransfected or Cw3-, Cw4-, or Cw6-transfected 221 cells in the absence or in the presence of mAbs to the indicated molecules. The ratio used was 1 : 1. The average of 4 independent experiments and standard deviation (mean ± SD) are indicated. ; .
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