Journal of Immunology Research / 2015 / Article / Tab 3

Review Article

Peptide-Based Treatment: A Promising Cancer Therapy

Table 3

Peptide-based vaccine in clinical application.

CancerTreatmentSampleStudy phaseYear AuthorReference

Pancreatic cancerWT1 peptide-based vaccine combined with gemcitabine32I2014Nishida et al.[27]
KIF20A-derived peptide in combination with gemcitabine9I2014Suzuki et al.[28]
Telomerase GV1001 vaccine together with gemcitabine21I2014Staff et al.[29]

Gastric cancer VEGFR1-1084 and VEGFR2-169 combined with S-1 and cisplatin22I/II2012Masuzawa et al.[30]
LY6K-177 peptide vaccine emulsified with Montanide ISA 516I2014Ishikawa et al.[31]

Prostate cancerPPV (2-4 positive peptides selected from 31 candidate peptides)100II2013Noguchi et al.[47]
IB-PAP-114-128 vaccine therapy2014Saif et al.[32]
A multipeptide, dual-adjuvant telomerase vaccine (GX301)11I/II2013Fenoglio et al.[48]

mrTNBCPPV18II2014Takahashi et al.[9]

Breast cancerP5 encapsulated in DOTAP-cholesterol-DOPE liposomes coadministered with CpG-ODN2014Mansourian et al.[33]
Optimized encapsulation of p5 into liposomes2014Shariat et al.[49]
An artificial long peptide consisting of SU18 and SU222014Ohtake et al.[34]
Combination therapy of E75 and GM-CSF187I/II2014Mittendorf et al.[35]
Multiepitope derived from ErbB-2 vaccine2014Gil et al.[36]

Colorectal cancerAtrial natriuretic peptide (ANP)2012Serafino et al.[37]
TCP-1 peptide2010Li et al.[38]
F56-VCR-NP2014Wang et al.[39]
Peptides from common bean NDF2014Luna Vital et al.[50]
Cep55/c10orf3 derived peptide vaccine2011Inoda et al.[51]
A cocktail vaccine of 5 peptides 18I2014Hazama et al.[52]
A combination of 7-peptide cocktail vaccine and tegafur-uracil plus leucovorin30I2014Okuno et al.[53]

Lung cancerDendritic cell vaccines pulsed with WT-1 peptide622013Takahashi et al.[40]
hTERT-targeting Vx-001 vaccine46II2014Kotsakis et al.[41]
A synthesized peptide Disruptin2014Ahsa et al.[42]
A ligand-independent peptide-based TREM1 inhibitor2014Sigalov[43]
Peptide fractions from high oleic acid soybean2013Rayaprolu et al.[54]
Peptides from venom of Eastern green mamba2014Conlon et al.[55]
LFC131-DOX NPs delivery system2014Chittasupho et al.[44]
TH10-DTX-NP2014Guan et al.[46]
BPP-decorated chitosan nanoparticles2014Wang et al.[45]

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.