Statins Increase the Frequency of Circulating CD4⁺FOXP3⁺ Regulatory T Cells in Healthy Individuals

Table 1

Variation in serum lipids levels during the observational period.

Variable	Day 0	Day 7	Day 30	Day 45
Tc (mmol/L)	4.50 (4.14–4.94)	4.37^** (3.75–4.89)	3.57^*** (3.13–4.32)	3.44^**** (2.90–3.85)
LDL-c (mm/L)	2.48 (1.94–2.90)	1.78^** (1.39–2.17)	1.5^**** (1.32–1.86)	1.83 (1.29–2.22)
HDL-c (mm/L)	1.06 (1.01–1.19)	0.98 (0.90–1.21)	1.16 (0.95–1.29)	1.16^* (1.01–1.32)
Tg (mm/L)	1.36 (1.0–2.06)	1.49 (1.16–1.71)	1.45 (1.01–2.01)	1.15^* (0.96–1.52)

Data are expressed as median (25th to 75th percentile). Tc: total cholesterol, LDL-c: low density lipoprotein cholesterol, HDL-c: high density lipoprotein cholesterol, Tg: triglycerides. as compared to baseline level. as compared to baseline level. as compared to baseline level. as compared to baseline level.