Serum CEACAM1 Elevation Correlates with Melanoma Progression and Failure to Respond to Adoptive Cell Transfer Immunotherapy

Figure 1

sCEACAM1 directly correlates with tumor burden in mice xenografts. 10 SCID-NOD mice were subcutaneously xenografted with human 009mel. Starting from the day of injection and through 3 weeks, serum samples were collected for further anti-human CEACAM1 ELISA and tumor volume was measured once weekly. The graph shows sCEACAM1 levels versus tumor volume.