Growth Modeling of the Maternal Cytokine Milieu throughout Normal Pregnancy: Macrophage-Derived Chemokine Decreases as Inflammation/Counterregulation Increases

Table 3

Cytokines with linear trimester as the time covariate, ordered by decreasing within-subject variance explained by adding trimester to the unconditional growth model (UGM).

Analyte	Estimated random slope variance	Estimated scatter variance around individual’s own trajectory	Within-subject variance explained by adding trimester to UGM	Estimated fixed effect from trimester
IL-1ra	0.04697	0.2513	0.27	0.1872	0.0054
IL-9	0.02779	0.1134	0.25	0.1618	0.0011
IL-12p40	0.08139	0.1892	0.24	0.1592	0.0446
sCD40L	0.09832	0.2156	0.14	0.2178	0.0122
IFNα2	0.002279	0.01625	0.20	0.05875	0.0002
IL-3	0.006149	0.06967	0.10	0.06972	0.0146