A Review of Intra- and Extracellular Antigen Delivery Systems for Virus Vaccines of Finfish

Table 3

DNA vaccines explored in fish.

Classification	Virus family	Pathogen	Abbreviation	Antigen	Protection	Reference
DNA viruses	Iridovirus	Red sea bream iridovirus	RSIV	Major capsid	Moderate	[185]
	Herpesviridae	Channel catfish virus (CCV)	CCV	ORF 6&59	Low	[186]
RNA virus	Rhabdoviridae	Viral hemorrhagic septicemia virus	VHSV	G	High	[95]
	Rhabdoviridae	Infectious hematopoietic necrosis virus	IHNV	G	High	[98, 187, 188]
	Rhabdoviridae	Spring viremia of carp virus	SVCV	G	High	[189, 190]
	Rhabdoviridae	Hirame rhabdovirus	HRV	G	High	[191]
	Birnaviridae	Infectious pancreatic necrosis virus	IPNV	SegA/VP2	Moderate	[103, 140]
	Orthomyxoviridae	Infectious salmon anemia virus	ISAV	HE	Moderate	[192]
	Togaviridae	Salmon alphavirus subtype 3	SAV-3	E2	Moderate	[157]
	Nodaviridae	Atlantic halibut nodavirus	ANHV	Capsid	Low	[193]

Protection was determined by postchallenge relative percent survival (RPS).