Review Article
Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells
Table 1
Human monocyte subsets and their murine counterparts.
| | Subset | Markers | Chemokine receptors | Main functions |
| | Human | | | | | Classical | CD14++CD16− | CCR2CX3CR1 | Immune response
Phagocytosis | | Intermediate | CD14+(+)CD16+ | CCR2CX3CR1 | Proinflammatory
Wound healing | | Nonclassical | CD14+CD16++ | CCR2CX3CR1 | Patrolling role
Fibrosis | | Mouse | | | | | Classical/intermediate () | Ly6C+CD11b+CD115+ | CCR2CX3CR1 | Proinflammatory
Phagocytosis | | Nonclassical | Ly6C−CD11b+CD115+ | CCR2CX3CR1 | Patrolling
Tissue repair |
|
|
() Murine Ly6C (classical/intermediate) monocytes are sometimes further divided into Ly6C and Ly6C monocytes.
|
