Clinical Study

HLA-01:03 Allele in Lung Transplant Recipients Correlates with Higher Chronic Lung Allograft Dysfunction Occurrence

Table 3

Main risk factors for CLAD according to Cox regression multivariate analysis on recipient diagnosis, HLA-G01:04~UTR3 haplotype, and HLA-E01:03 allele (HR, hazard ratio; CI, confidence interval).

Estimated HR (95% CI) value

Diagnosis
 Cystic fibrosis Baseline0.000
 Emphysema8.612 (3.113–23.824)0.000
 Fibrosis1.515 (0.362–6.335)0.569
 Others2.897 (0.822–10.214)0.098
HLA-G01:04~UTR32.567 (0.889–7.412)0.071
HLA-E01:03 3.563 (1.016–12.488)0.047