CXCR3, CCR5, and CRTH2 Chemokine Receptor Expression in Lymphocytes Infiltrating Thyroid Nodules with Coincident Hashimoto’s Thyroiditis Obtained by Fine Needle Aspiration Biopsy

Table 3

Intracellular cytokine expression in lymphocytes from peripheral blood.

	Patients (thyroid nodules with Hashimoto’s thyroiditis)	Controls (pure thyroid nodules)	value
IFN-gamma (%)^2	33.01 ± 13.01	33.94 ± 11.96	n.s.
TNF-alpha (%)^2	47.61 ± 13.38	50.35 ± 12.98	n.s.
IL-2 (%)^2	39.2 ± 16.62	38.54 ± 11.85	n.s.
IL-4 (%)^1	5.6 (3.5–7.78)	6.4 (4.05 ± 9.03)	n.s.
IL-10 (%)^1	13.45 (7.65–24.5)	16.3 (9.8–22.92)	n.s.
IL-12 (%)^2	24.31 ± 14.16	30.92 ± 15.40	0.045

Expressed as lymphocyte ratio with expression of individual cytokine, ¹median (lower quartile-upper quartile), ²mean ± standard deviation, IFN: interferon, TNF: tumor necrosis factor, and IL: interleukin.