Link-Polymorphism of 5-HTT Promoter Region Is Associated with Autoantibodies in Patients with Systemic Lupus Erythematosus

Figure 1

5-HTTLPR genotypes in SLE patients and HCs. (a) The frequency of 5-HTTLPR genotypes in HCs and SLE patients; (b) the frequency of 5-HTTLPR alleles in HCs and SLE patients. (c) The frequency of SS genotype was significantly higher than LL/LS genotype in SLE patients with positive anti-Sm antibody; (d) the frequency of SS genotype was significantly higher than LL/LS genotype in SLE patients with positive anti-U1RNP antibody; (e) the frequency of S allele was significantly higher in SLE patients with positive anti-U1RNP antibody; (f) the frequency of SS genotype was significantly higher than the other 2 genotypes in SLE patients with positive anti-Sm antibody.

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