Mast Cell-Derived Exosomes Promote Th2 Cell Differentiation via OX40L-OX40 Ligation

Figure 4

Mechanism of BMMC-exosome function in naive CD4⁺ T cells. Exosomes and T cells were stained with Dil (red-orange) and Dio (green), respectively. During the first 24 hours, exosomes were found to adhere to T cells and no endocytosis was observed. The picture was taken 12 hours after the coculture at a magnification ×400.