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Journal of Immunology Research
Volume 2016 (2016), Article ID 4048235, 17 pages
http://dx.doi.org/10.1155/2016/4048235
Research Article

Low Dose BCG Infection as a Model for Macrophage Activation Maintaining Cell Viability

1Department of Pathology and Immunology, Centre Medical Universitaire (CMU), Faculty of Medicine, University of Geneva, Geneva, Switzerland
2Laboratory of Integrative Immunology, National Institute of Respiratory Diseases “Ismael Cosio Villegas”, Mexico City, Mexico
3Department of Cell Physiology and Metabolism, Centre Medical Universitaire (CMU), Faculty of Medicine, University of Geneva, Geneva, Switzerland

Received 18 May 2016; Revised 26 August 2016; Accepted 15 September 2016

Academic Editor: Ethan M. Shevach

Copyright © 2016 Leslie Chávez-Galán et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure 1: Pro-caspase 1 is detected earlier in macrophages infected at MOI 0.1 than MOI 1. Western blot analyses for pro-caspase-1 p45, caspase-1 p20 and tubulin of cells infected at MOI 1 and MOI 0.1 at different time points. Bars indicate mean +/- SEM from three independent experiments. **P<0.01, *P<0.03.

  1. Supplementary Material