Table of Contents Author Guidelines Submit a Manuscript
Journal of Immunology Research
Volume 2016 (2016), Article ID 4131324, 12 pages
http://dx.doi.org/10.1155/2016/4131324
Research Article

Yeast Surface-Displayed H5N1 Avian Influenza Vaccines

1Department of Biomedical Engineering, Watson School of Engineering and Applied Sciences, Binghamton University, State University of New York (SUNY), Binghamton, NY 13902, USA
2Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA

Received 24 June 2016; Revised 25 September 2016; Accepted 19 October 2016

Academic Editor: Peirong Jiao

Copyright © 2016 Han Lei et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. O. A. L. Cintra and L. C. Rey, “Safety, immunogenicity and efficacy of influenza vaccine in children,” Jornal de Pediatria, vol. 82, no. 3, supplement, pp. S83–S90, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. R. Rappuoli and P. R. Dormitzer, “Influenza: options to improve pandemic preparation,” Science, vol. 336, no. 6088, pp. 1531–1533, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. R. J. Webby, D. R. Perez, J. S. Coleman et al., “Responsiveness to a pandemic alert: use of reverse genetics for rapid development of influenza vaccines,” The Lancet, vol. 363, no. 9415, pp. 1099–1103, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. J. Crawford, B. Wilkinson, A. Vosnesensky et al., “Baculovirus-derived hemagglutinin vaccines protect against lethal influenza infections by avian H5 and H7 subtypes,” Vaccine, vol. 17, no. 18, pp. 2265–2274, 1999. View at Publisher · View at Google Scholar · View at Scopus
  5. W. Gao, A. C. Soloff, X. Lu et al., “Protection of mice and poultry from lethal H5N1 avian influenza virus through adenovirus-based immunization,” Journal of Virology, vol. 80, no. 4, pp. 1959–1964, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Tang, J. A. Harp, and R. D. Wesley, “Recombinant adenovirus encoding the HA gene from swine H3N2 influenza virus partially protects mice from challenge with heterologous virus: A/HK/1/68 (H3N2),” Archives of Virology, vol. 147, no. 11, pp. 2125–2141, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. R. D. Wesley and K. M. Lager, “Evaluation of a recombinant human adenovirus-5 vaccine administered via needle-free device and intramuscular injection for vaccination of pigs against swine influenza virus,” American Journal of Veterinary Research, vol. 66, no. 11, pp. 1943–1947, 2005. View at Publisher · View at Google Scholar · View at Scopus
  8. K. R. Van Kampen, Z. Shi, P. Gao et al., “Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humans,” Vaccine, vol. 23, no. 8, pp. 1029–1036, 2005. View at Publisher · View at Google Scholar · View at Scopus
  9. E. Nwanegbo, E. Vardas, W. Gao et al., “Prevalence of neutralizing antibodies to adenoviral serotypes 5 and 35 in the adult populations of the gambia, South Africa, and the United States,” Clinical and Diagnostic Laboratory Immunology, vol. 11, no. 2, pp. 351–357, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. A. R. Pinto, J. C. Fitzgerald, W. Giles-Davis, G. P. Gao, J. M. Wilson, and H. C. J. Ertl, “Induction of CD8+ T cells to an HIV-1 antigen through a prime boost regimen with heterologous E1-deleted adenoviral vaccine carriers,” The Journal of Immunology, vol. 171, no. 12, pp. 6774–6779, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. S. F. Farina, G.-P. Gao, Z. Q. Xiang et al., “Replication-defective vector based on a chimpanzee adenovirus,” Journal of Virology, vol. 75, no. 23, pp. 11603–11613, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. W. Gao, P. D. Robbins, and A. Gambotto, “Human adenovirus type 35: nucleotide sequence and vector development,” Gene Therapy, vol. 10, no. 23, pp. 1941–1949, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. Y.-F. Mei, J. Skog, K. Lindman, and G. Wadell, “Comparative analysis of the genome organization of human adenovirus 11, a member of the human adenovirus species B, and the commonly used human adenovirus 5 vector, a member of species C,” Journal of General Virology, vol. 84, no. 8, pp. 2061–2071, 2003. View at Publisher · View at Google Scholar · View at Scopus
  14. J. W. Shiver and E. A. Emini, “Recent advances in the development of HIV-1 vaccines using replication-incompetent adenovirus vectors,” Annual Review of Medicine, vol. 55, pp. 355–372, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. M. Cherbonnel, J. Rousset, and V. Jestin, “Strategies to improve protection against low-pathogenicity H7 avian influenza virus infection using DNA vaccines,” Avian Diseases, vol. 47, no. 3, supplement, pp. 1181–1186, 2003. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Kodihalli, J. R. Haynes, H. L. Robinson, and R. G. Webster, “Cross-protection among lethal H5N2 influenza viruses induced by DNA vaccine to the hemagglutinin,” Journal of Virology, vol. 71, no. 5, pp. 3391–3396, 1997. View at Google Scholar · View at Scopus
  17. S. Kodihalli, D. L. Kobasa, and R. G. Webster, “Strategies for inducing protection against avian influenza A virus subtypes with DNA vaccines,” Vaccine, vol. 18, no. 23, pp. 2592–2599, 2000. View at Publisher · View at Google Scholar · View at Scopus
  18. C. W. Lee, D. A. Senne, and D. L. Suarez, “Development of hemagglutinin subtype-specific reference antisera by DNA vaccination of chickens,” Avian Diseases, vol. 47, supplement 3, pp. 1051–1056, 2003. View at Publisher · View at Google Scholar · View at Scopus
  19. X. Saelens, P. Vanlandschoot, W. Martinet et al., “Protection of mice against a lethal influenza virus challenge after immunization with yeast-derived secreted influenza virus hemagglutinin,” European Journal of Biochemistry, vol. 260, no. 1, pp. 166–175, 1999. View at Publisher · View at Google Scholar · View at Scopus
  20. A. C. Stubbs, K. S. Martin, C. Coeshott et al., “Whole recombinant yeast vaccine activates dendritic cells and elicits protective cell-mediated immunity,” Nature Medicine, vol. 7, no. 5, pp. 625–629, 2001. View at Publisher · View at Google Scholar · View at Scopus
  21. Y. Tamara, M. Ohtsuka, K. Kato et al., “Application of the arming system for the expression of the 380R antigen from red sea bream iridovirus (RSIV) on the surface of yeast cells: a first step for the development of an oral vaccine,” Biotechnology Progress, vol. 22, no. 4, pp. 949–953, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. S. Shibasaki, W. Aoki, T. Nomura et al., “An oral vaccine against candidiasis generated by a yeast molecular display system,” Pathogens and Disease, vol. 69, no. 3, pp. 262–268, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Shibasaki, W. Aoki, and M. Ueda, “Biodefense-new stage in the molecular controlling of immune system,” Yakugaku Zasshi, vol. 133, no. 11, pp. 1143–1144, 2013. View at Publisher · View at Google Scholar · View at Scopus
  24. K. Ye, S. Shibasaki, M. Ueda et al., “Construction of an engineered yeast with glucose-inducible emission of green fluorescence from the cell surface,” Applied Microbiology and Biotechnology, vol. 54, no. 1, pp. 90–96, 2000. View at Publisher · View at Google Scholar · View at Scopus
  25. S. Shibasaki, M. Ueda, K. Ye et al., “Creation of cell surface-engineered yeast that display different fluorescent proteins in response to the glucose concentration,” Applied Microbiology and Biotechnology, vol. 57, no. 4, pp. 528–533, 2001. View at Publisher · View at Google Scholar · View at Scopus
  26. E. T. Boder and K. D. Wittrup, “Yeast surface display for screening combinatorial polypeptide libraries,” Nature Biotechnology, vol. 15, no. 6, pp. 553–557, 1997. View at Publisher · View at Google Scholar · View at Scopus
  27. E. T. Boder and K. D. Wittrup, “Yeast surface display for directed evolution of protein expression, affinity, and stability,” Methods Enzymol, vol. 328, pp. 430–444, 2000. View at Publisher · View at Google Scholar
  28. I. Chen, B. M. Dorr, and D. R. Liu, “A general strategy for the evolution of bond-forming enzymes using yeast display,” Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 28, pp. 11399–11404, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. N. Fukuda, J. Ishii, S. Shibasaki, M. Ueda, H. Fukuda, and A. Kondo, “High-efficiency recovery of target cells using improved yeast display system for detection of protein-protein interactions,” Applied Microbiology and Biotechnology, vol. 76, no. 1, pp. 151–158, 2007. View at Publisher · View at Google Scholar · View at Scopus
  30. T. Shigemori, M. Nagayama, J. Yamada et al., “Construction of a convenient system for easily screening inhibitors of mutated influenza virus neuraminidases,” FEBS Open Bio, vol. 3, pp. 484–489, 2013. View at Publisher · View at Google Scholar · View at Scopus
  31. T. Han, J. Sui, A. S. Bennett et al., “Fine epitope mapping of monoclonal antibodies against hemagglutinin of a highly pathogenic H5N1 influenza virus using yeast surface display,” Biochemical and Biophysical Research Communications, vol. 409, no. 2, pp. 253–259, 2011. View at Publisher · View at Google Scholar · View at Scopus
  32. S. Jin, C. J. Issel, and R. C. Montelaro, “Serological method using recombinant S2 protein to differentiate equine infectious anemia virus (EIAV)-infected and EIAV-vaccinated horses,” Clinical and Diagnostic Laboratory Immunology, vol. 11, no. 6, pp. 1120–1129, 2004. View at Publisher · View at Google Scholar · View at Scopus
  33. S. Jin, C. Chen, and R. C. Montelaro, “Equine infectious anemia virus Gag p9 function in early steps of virus infection and provirus production,” Journal of Virology, vol. 79, no. 14, pp. 8793–8801, 2005. View at Publisher · View at Google Scholar · View at Scopus
  34. S. Jin, E. Ellis, J. V. Veetil, H. Yao, and K. Ye, “Visualization of human immunodeficiency virus protease inhibition using a novel Förster resonance energy transfer molecular probe,” Biotechnology Progress, vol. 27, no. 4, pp. 1107–1114, 2011. View at Publisher · View at Google Scholar · View at Scopus
  35. Y. Watanabe, M. S. Ibrahim, H. F. Ellakany et al., “Acquisition of human-type receptor binding specificity by new H5N1 influenza virus sublineages during their emergence in birds in Egypt,” PLoS Pathogens, vol. 7, no. 5, Article ID e1002068, 2011. View at Publisher · View at Google Scholar · View at Scopus
  36. H. Yang, P. J. Carney, J. C. Chang, J. M. Villanueva, and J. Stevens, “Structural analysis of the hemagglutinin from the recent 2013 H7N9 influenza virus,” Journal of Virology, vol. 87, no. 22, pp. 12433–12446, 2013. View at Publisher · View at Google Scholar · View at Scopus
  37. S. Jin, H. Yao, P. Krisanarungson, A. Haukas, and K. Ye, “Porous membrane substrates offer better niches to enhance the wnt signaling and promote human embryonic stem cell growth and differentiation,” Tissue Engineering Part A, vol. 18, no. 13-14, pp. 1419–1430, 2012. View at Publisher · View at Google Scholar · View at Scopus
  38. K. Ye, S. Jin, K. Bratic, and J. S. Schultz, “Surface display of a glucose binding protein,” Journal of Molecular Catalysis B: Enzymatic, vol. 28, no. 4–6, pp. 201–206, 2004. View at Publisher · View at Google Scholar · View at Scopus
  39. K. Ye and S. Jin, “Potent and specific inhibition of retrovirus production by coexpression of multiple siRNAs directed against different regions of viral genomes,” Biotechnology Progress, vol. 22, no. 1, pp. 45–52, 2006. View at Publisher · View at Google Scholar · View at Scopus
  40. J. C. Jones, E. W. Settles, C. R. Brandt, and S. Schultz-Cherry, “Virus aggregating peptide enhances the cell-mediated response to influenza virus vaccine,” Vaccine, vol. 29, no. 44, pp. 7696–7703, 2011. View at Publisher · View at Google Scholar · View at Scopus
  41. M. A. Jabbar, N. Sivasubramanian, and D. P. Nayak, “Influenza viral (A/WSN/33) hemagglutinin is expressed and glycosylated in the yeast Saccharomyces cerevisiae,” Proceedings of the National Academy of Sciences of the United States of America, vol. 82, no. 7, pp. 2019–2023, 1985. View at Publisher · View at Google Scholar · View at Scopus
  42. Ts. Fülöp, Handbook on Immunosenescence: Basic Understanding and Clinical Applications, Springer, New York, NY, USA, 2009.
  43. V. C. Huber, R. M. McKeon, M. N. Brackin et al., “Distinct contributions of vaccine-induced immunoglobulin G1 (IgG1) and IgG2a antibodies to protective immunity against influenza,” Clinical and Vaccine Immunology, vol. 13, no. 9, pp. 981–990, 2006. View at Publisher · View at Google Scholar · View at Scopus
  44. L. Bungener, F. Geeraedts, W. Ter Veer, J. Medema, J. Wilschut, and A. Huckriede, “Alum boosts TH2-type antibody responses to whole-inactivated virus influenza vaccine in mice but does not confer superior protection,” Vaccine, vol. 26, no. 19, pp. 2350–2359, 2008. View at Publisher · View at Google Scholar · View at Scopus
  45. J.-M. Song, J. Hossain, D.-G. Yoo et al., “Protective immunity against H5N1 influenza virus by a single dose vaccination with virus-like particles,” Virology, vol. 405, no. 1, pp. 165–175, 2010. View at Publisher · View at Google Scholar · View at Scopus
  46. M. Prabakaran, A. B. Kolpe, F. He, and J. Kwang, “Cross-protective efficacy of bivalent recombinant baculoviral vaccine against heterologous influenza H5N1 challenge,” Vaccine, vol. 31, no. 10, pp. 1385–1392, 2013. View at Publisher · View at Google Scholar · View at Scopus
  47. K. Blanchfield, R. P. Kamal, W.-P. Tzeng et al., “Recombinant influenza H7 hemagglutinins induce lower neutralizing antibody titers in mice than do seasonal hemagglutinins,” Influenza and Other Respiratory Viruses, vol. 8, no. 6, pp. 628–635, 2014. View at Publisher · View at Google Scholar · View at Scopus
  48. X. Lu, T. M. Tumpey, T. Morken, S. R. Zaki, N. J. Cox, and J. M. Katz, “A mouse model for the evaluation of pathogenesis and immunity to influenza A (H5N1) viruses isolated from humans,” Journal of Virology, vol. 73, no. 7, pp. 5903–5911, 1999. View at Google Scholar · View at Scopus
  49. T. M. Tumpey, M. Renshaw, J. D. Clements, and J. M. Katz, “Mucosal delivery of inactivated influenza vaccine induces B-cell-dependent heterosubtypic cross-protection against lethal influenza a H5N1 virus infection,” Journal of Virology, vol. 75, no. 11, pp. 5141–5150, 2001. View at Publisher · View at Google Scholar · View at Scopus
  50. F.-S. Quan, Y.-C. Kim, J.-M. Song et al., “Long-term protective immunity from an influenza virus-like particle vaccine administered with a microneedle patch,” Clinical and Vaccine Immunology, vol. 20, no. 9, pp. 1433–1439, 2013. View at Publisher · View at Google Scholar · View at Scopus
  51. S.-M. Kang, D.-G. Yoo, A. S. Lipatov et al., “Induction of long-term protective immune responses by influenza H5N1 virus-like particles,” PLoS ONE, vol. 4, no. 3, Article ID e4667, 2009. View at Publisher · View at Google Scholar · View at Scopus
  52. Y. D. Gwon, S. Kim, Y. Cho et al., “Immunogenicity of virus like particle forming baculoviral DNA vaccine against pandemic influenza H1N1,” PLoS ONE, vol. 11, no. 5, Article ID e0154824, 2016. View at Publisher · View at Google Scholar
  53. J. L. Wasilenko, L. Sarmento, S. Spatz, and M. Pantin-Jackwood, “Cell surface display of highly pathogenic avian influenza virus hemagglutinin on the surface of Pichia pastoris cells using α-agglutinin for production of oral vaccines,” Biotechnology Progress, vol. 26, no. 2, pp. 542–547, 2010. View at Publisher · View at Google Scholar · View at Scopus
  54. R. De Smet, L. Allais, and C. A. Cuvelier, “Recent advances in oral vaccine development: yeast-derived β-glucan particles,” Human Vaccines and Immunotherapeutics, vol. 10, no. 5, pp. 1309–1318, 2014. View at Publisher · View at Google Scholar · View at Scopus