Research Article

Evaluation of Multiple Immunoassay Technology Platforms to Select the Anti-Drug Antibody Assay Exhibiting the Most Appropriate Drug and Target Tolerance

Figure 1

Schematic representation of different scenarios that can occur in the bridging assay. (a) Presence of ADA leading to a positive signal. (b) Drug interference leading to false negative signal. (c) Target interference leading to false positive signal.
(a)
(b)
(c)