Monocyte-Derived Macrophages Are Impaired in Myelodysplastic Syndrome

Figure 3

Phagocytosis of monocyte-induced macrophages as demonstrated by fluorescent microspheres. (a) Phagocytic capacity of differentiated macrophages derived from peripheral blood from patients with MDS and normal controls was tested with fluorescent microspheres by flow cytometry. In the picture, the left represents the macrophages not engulfing the fluorescent microspheres; the right represents the macrophages engulfing the fluorescent microspheres. R3 suggests that the macrophages are swallowing a fluorescent microsphere; R4 suggests that the macrophages are swallowing two fluorescent microspheres; R5 suggests that the macrophages are swallowing three fluorescent microspheres; R6 suggests that the macrophages are swallowing four fluorescent microspheres. (b) The PI and PP of monocyte-induced macrophages from MDS and normal controls are shown, respectively ().

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