Research Article

Identification of Novel Vaccine Candidates against Campylobacter through Reverse Vaccinology

Table 3

Potential vaccine candidates selected after the whole bioinformatic analysis process including Vaxign and VaxiJen programs, BCPreds and AAP algorithms, and blast analyses. Of 1758 ORFs encoded by C. jejuni, strain 81-176 genome, 14 proteins were selected as vaccine candidates.

Protein accessionDescriptionLocalizationID

YP_001000562.1Flagellin protein familyExtracellular
YP_999769.1Flagellar hook proteinExtracellularFlgE-1
YP_001001115.1Flagellar hook-associated proteinExtracellularFlgK
YP_001000153.1TonB-dependent receptor, putative, degenerateOMP
YP_001000945.1N-Acetylmuramoyl-L-alanine amidaseOMP
YP_001000437.1Putative OMPOMP
YP_999838.1Hypothetical proteinOMP
YP_999817.1Hypothetical proteinOMP
YP_001000383.1Flagellar basal body L-ring proteinOMPFlgH
YP_001000935.1Major OMPOMPPorA
YP_001001008.1Phospholipase AOMPPldA
YP_001001257.1TonB-dependent heme receptorOMPChuA
YP_001000663.1Surface-exposed lipoproteinOMPJlpA
YP_001000261.1Hypothetical proteinOMP