Serum HMGB1 Serves as a Novel Laboratory Indicator Reflecting Disease Activity and Treatment Response in Ankylosing Spondylitis Patients

Table 2

Spearman’s correlation analysis between serum HMGB1 and clinical parameters of the 147 AS patients, including the baseline and the follow-up time points.

	HMGB1	BASDAI	BASFI	ASDAS-ESR	ASDAS-CRP	CRP	ESR
HMGB1		0.304	0.184	0.275	0.251	0.132	0.162
BASDAI			0.635	0.668	0.678	0.364	0.385
BASFI				0.595	0.607	0.396	0.418
ASDAS-ESR					0.884	0.668	0.797
ASDAS-CRP						0.738	0.669
CRP							0.761

BASDAI: Bath AS Disease Activity Index, BASFI: Bath AS Functional Index, ASDAS: AS Disease Activity Score, ESR: erythrocyte sedimentation rate, and CRP: C-reactive protein. Values are shown as . is determined by Spearman’s correlation analysis. . .