Review Article

Function of G-Protein-Coupled Estrogen Receptor-1 in Reproductive System Tumors

Table 1

The effect of GPER-1 in reproductive system tumors.

Cancer typesER positive breast cancerER negative breast cancerTriple negative breast cancerOvarian cancerTesticular cancerProstate cancer

Proliferation+24, 31+28, 31+40, 41+47, 48, 49, 50+55, 56, 57−61, 62
−17, 25, 52−23, 36, 37−51, 52

Migration and metastasis+18, 21, 22, 31, 15, 32+27, 28, 29+41+48, 49//

Poor survival+20, 16−36+38, 39, 40+46//

Drug resistance+19, 20, 21+26////