Research Article

Antigen-Specific IFN-γ Responses Correlate with the Activity of M. tuberculosis Infection but Are Not Associated with the Severity of Tuberculosis Disease

Table 2

Correlations between IFN- responses and TB disease severity.

TB characteristicsrho/-valueIFN-IFN-IFN-IFN-QFT results

Forms of pulmonary pathologyrho0.045−0.2390.352 −0.235−0.091
value0.7130.0800.0040.0840.521

TB extentrho0.050−0.1650.395−0.156−0.060
value0.6940.2530.0010.2860.650

The degree of pulmonary destructionrho0.108−0.080−0.226−0.063−0.024
value0.4850.5760.0950.6430.842

The degree of bacteria excretionrho0.077−0.201−0.125−0.209−0.213
value0.5790.1440.3980.1250.121

The degree of intoxicationrho0.084−0.178−0.195−0.173−0.099
value0.5580.2120.1560.2270.497

Agerho0.391−0.0200.101−0.066−0.094
value0.0010.8550.4970.6330.516

Correlations were analysed using nonparametric Spearman test with Benjamini-Hochberg correction. Significant correlations are shown in bold.