Antigen-Specific IFN-γ Responses Correlate with the Activity of M. tuberculosis Infection but Are Not Associated with the Severity of Tuberculosis Disease
Table 2
Correlations between IFN- responses and TB disease severity.
TB characteristics
rho/-value
IFN-
IFN-
IFN-
IFN-
QFT results
Forms of pulmonary pathology
rho
0.045
−0.239
−0.352
−0.235
−0.091
value
0.713
0.080
0.004
0.084
0.521
TB extent
rho
0.050
−0.165
−0.395
−0.156
−0.060
value
0.694
0.253
0.001
0.286
0.650
The degree of pulmonary destruction
rho
0.108
−0.080
−0.226
−0.063
−0.024
value
0.485
0.576
0.095
0.643
0.842
The degree of bacteria excretion
rho
0.077
−0.201
−0.125
−0.209
−0.213
value
0.579
0.144
0.398
0.125
0.121
The degree of intoxication
rho
0.084
−0.178
−0.195
−0.173
−0.099
value
0.558
0.212
0.156
0.227
0.497
Age
rho
0.391
−0.020
0.101
−0.066
−0.094
value
0.001
0.855
0.497
0.633
0.516
Correlations were analysed using nonparametric Spearman test with Benjamini-Hochberg correction. Significant correlations are shown in bold.