Research Article

Bone Marrow Mesenchymal Stem Cells Enhance the Differentiation of Human Switched Memory B Lymphocytes into Plasma Cells in Serum-Free Medium

Table 1

Expression of CD31, CD38, CD39 and CD138 among plasma cells population on day 20.

ConditionPopulation1Cells2 (%)
CD31CD38CD39CD138

21% O2
 L4.5A19,2 ± 4,823,0 ± 6,893,3 ± 1,044,9 ± 4,8
B57,8 ± 4,449,4 ± 8,993,1 ± 4,457,3 ± 8,0
 MSCA26,2 ± 4,440,8 ± 5,777,9 ± 7,611,8 ± 6,2
B87,4 ± 2,386,3 ± 5,697,0 ± 2,474,9 ± 6,0
8% O2
 L4.5A14,5 ± 4,615,5 ± 4,891,6 ± 1,424,0 ± 6,4
B62,6 ± 2,342,7 ± 6,097,6 ± 0,952,5 ± 7,6
 MSCA23,9 ± 3,336,7 ± 2,476,2 ± 5,17,3 ± 1,7
B87,1 ± 1,789,9 ± 1,298,2 ± 1,378,3 ± 4,1

1Analyses were done according to the populations A and B as describes respectively as and as showed in Figures 5 and 6.
2The proportion of cells positive for each marker was determined for 5 independent experiments by cytometry analysis as showed in Figure 6. Data are mean ± S.E.M.