Journal of Immunology Research / 2016 / Article / Tab 1

Research Article

Downregulation of p70S6K Enhances Cell Sensitivity to Rapamycin in Esophageal Squamous Cell Carcinoma

Table 1

Effects of rapamycin alone or combined with p70S6K siRNA on the growth of ESCC xenografts in nude mice ().

GroupsAnimal weight (g)Volume before therapy (mm3)Volume after therapy (mm3)Inhibition rate (%)

Control18.80 ± 1.9282.68 ± 11.941907.86 ± 326.000
Rapamycin20.07 ± 1.5063.12 ± 23.18546.62 ± 94.5370.35
p70S6K siRNA19.54 ± 0.6387.99 ± 9.081658.72 ± 159.5813.06
siRNA + Rapa20.12 ± 1.2861.14 ± 15.4267.03 ± 33.8896.49

, compared with control group.

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