Overexpression of MMP-3 and uPA with Diminished PAI-1 Related to Metastasis in Ductal Breast Cancer Patients Attending a Public Hospital in Mexico City
Table 1
Clinical and pathological characterization of breast cancer patients participating in the study.
Clinical-pathological characteristics
All cases (118) Ductal breast cancer
%
Groups according to metastasis
N0
N1
Cases (54)
%
Cases (64)
%
Age (years)
≤55
77
65
32
60
45
70
>55
41
35
22
40
19
30
Tumor size
T1 (<2 cm)
25
21
13
24
12
19
T2 (2–5 cm)
79
67
35
65
44
69
T3 (>5 cm)
14
12
6
11
8
12
Tumor grade (SBR)
I
29
25
17
31
12
19
II
65
55
29
54
36
56
III
24
20
8
15
16
25
Nodal status
pN0
54
46
54
100
pN1
30
25
30
47
pN2
28
24
28
44
pN3
6
5
6
9
Mononuclear infiltrate
Positive
85
72
39
72
46
72
Negative
33
28
15
28
18
28
Desmoplasia
Positive
42
36
19
35
23
36
Negative
76
64
35
65
41
64
Molecular subtype
Luminal A
29
25
12
22
17
27
Luminal B
46
39
17
31
29
45
Her2
25
21
16
30
9
14
Triple negative
18
24
9
17
9
14
Patients (), with invasive ductal breast cancer, were sorted in two groups based on presence/absence of metastasis in nearest ganglia. N0 = without metastasis in ganglia nodes. N1 = with at least one metastatic ganglia node.
