Overexpression of MMP-3 and uPA with Diminished PAI-1 Related to Metastasis in Ductal Breast Cancer Patients Attending a Public Hospital in Mexico City

Table 2

Semiquantitation of protein samples analyzed in patients with ductal breast cancer.

Protein	Group			value
	N0; IOD (mean)	N1; IOD (mean)	Nodal metastatic; IOD (mean)
				N0 versus N1	N1 versus nodal
MMP-1	15,500	20,200	16,600
MMP-3	22,300	28,600	22,200	<0.05	<0.05
MMP-9	11,600	13,200	20,900		<0.05
TIMP-1	10,600	12,300	17,800
UPA	26,000	37,600	39,400	<0.05
UPAR	19,800	20,000	21,800
PAI-1	25,100	19,200	18,000

Semiquantitation of the signal was performed using ImageJ software and statistical significance acquired by applying the Mann–Whitney test . N0 = without metastasis in ganglia nodes. N1 = with at least one metastatic ganglia node.