Circulating Regulatory T-Cells in Monoclonal Gammopathies of Uncertain Significance and Multiple Myeloma: In Search of a Role

Table 1

Main patients’ characteristics at study entry.

	MM (39 patients)	MGUS (44 patients)
Age (years)
(median; range)	69 (37–90)	65 (39–87)
Gender (number; %)
Male	18 (46%)	25 (57%)
Female	21 (54%)	19 (43%)
International staging system (ISS) (number; %)
ISS-1	9 (23%)
ISS-2	19 (49%)
ISS-3	11 (28%)
MM/MGUS subtype (number; %)
IgG	28 (72%)	32 (73%)
IgA	11 (28%)	8 (18%)
IgM	—	4 (9%)
Serum M-protein (g/dL)
(median; range)	2.9 (2.1–5.3)	1.1 (0.2–1.9)
Percentage of BM plasma cells
(median; range)	36 (23–85)	7 (1–10)

BM: bone marrow; MM: multiple myeloma; MGUS: monoclonal gammopathies of uncertain significance.