Genetic Polymorphisms of IL17 and Chagas Disease in the South and Southeast of Brazil

Table 4

Genotype frequencies of IL17F rs753780 in Brazilian Chagas disease patients with chronic cardiomyopathy, stratified according to gender.

Gender	IL17F T7488C	Without; LVSD; (%)	Mild/moderate; LVSD; (%)	Severe; LVSD; (%)	Without CCC; (%)	Controls; (%)
Male	TT	40 (86.96)	21 (91.3)	19 (65.5)	22 (45.8)	64 (86.49)
	TC	6 (13.04)	2 (8.7)	10 (34.5)	2 (4.2)	10 (13.51)
Female	TT	58 (92.06)	24 (82.8)	20 (90.9)	20 (41.7)	68 (89.47)
	TC	5 (7.94)	5 (17.2)	2 (9.1)	4 (8.3)	8 (10.53)

CCC, chronic Chagas cardiomyopathy; LVSD, left ventricular systolic dysfunction; OR, odds ratio; CI, confidence interval.
Data adjusted by age.
Only significant results are showed.
OR = 4.82 and 95% CI = 1.55–14.98; severe LVSD versus without LVSD.
OR = 6.02 and 95% CI = 1.18–30.78; severe LVSD versus mild/moderate LVSD.
OR = 6.70 and 95% CI = 1.19–37.53; severe LVSD versus without CCC patients.
OR = 3.40 and 95% CI = 1.24–9.31; severe LVSD versus controls.