Journal of Immunology Research / 2017 / Article / Tab 4

Research Article

Donor-Specific Anti-Human Leukocyte Antigen Antibodies Predict Prolonged Isolated Thrombocytopenia and Inferior Outcomes of Haploidentical Hematopoietic Stem Cell Transplantation

Table 4

Multivariate analysis of factors associated with transplant outcomes.

HR95% CI value

Prolonged isolated
thrombocytopenia
 Infused CD34+ cells ≥ median0.4810.232–1.0010.050
 DSA
  MFI ≥ 10003.2621.339–7.9460.009
TRM
 Disease status1.753(0.985–3.118)0.056
 Infused CD4+ cells ≥ median1.899(1.079–3.340)0.026
 DSA
  MFI ≥ 10002.320(1.169–4.426)0.044
Relapse
 Disease status3.882(2.103–7.166)<0.001
 HLA-DP2.552(1.139–5.742)0.0230
DFS
 Disease status2.667(1.761–4.038)<0.001
 cGVHD0.622(0.423–0.916)<0.016
OS
 Disease status2.504(1.643–3.817)<0.001
 cGVHD0.612(0.413–0.908)0.015
 DSA
  MFI ≥ 10001.220(0.998–2.138)0.082