Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use

Figure 1

Matured phenotype of IL-15 designer DC. Surface expressions of CD80, CD83, CD86, CD14, HLA-DR, CCR7, IL-15, CD40, CD70, CD209, and OX-40L on IL-15 EP DC (dashed-lined histogram) or IL-15/IL-15Rα EP DC (thin-lined black histogram) were compared 4 h after electroporation with mock EP DC (dark-grey-filled histogram) and isotype controls (light-grey-filled histogram). Histogram overlays are shown for one representative donor out of six independent donors. CCR7, C-C chemokine receptor type 7; HLA, human leukocyte antigen; IL, interleukin.