Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use

Figure 2

Migratory capacity of IL-15 designer DC. Bars depict the mean percentage (±SEM; ) CCL19/CCL21-mediated migration of mock EP DC (white bar), IL-15 EP DC (grey bar), and IL-15/IL-15Rα EP DC (black bar) 4 h after electroporation in a 3 h transwell chemotaxis assay. DC migration was calculated according to the equation specified in the Material and Methods. DC, dendritic cells; EP, electroporation; cpm, counts per minute; IL, interleukin; IL-15Rα, interleukin-15 receptor alpha; SEM, standard error of mean.