Research Article

Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use

Table 1

Cytokine secretion (±SEM) in 24 h washed-out supernatant by IL-15 designer DC. DC: dendritic cell; DL: detection limit; EP: electroporated; IFN: interferon; IL: interleukin; SEM: standard error of mean; TNF: tumor necrosis factor. (compared to mock EP DC) ().

Mock EP DCIL-15 EP DCIL-15/IL-15Rα EP DC
(pg/mL)(pg/mL)(pg/mL)

IFN-α2a0 ± 00 ± 00 ± 0
IFN-γ19 ± 2 < DL54 ± 352 ± 3
TNF-α62 ± 375 ± 374 ± 5
IL-40 ± 00 ± 00 ± 0
IL-6176 ± 21167 ± 18167 ± 19
IL-100 ± 00 ± 00 ± 0
IL-170 ± 00 ± 00 ± 0
IL-18113 ± 80103 ± 73104 ± 74