Journal of Immunology Research / 2017 / Article / Tab 2

Research Article

Polymorphisms of IL12RB2 May Affect the Natural History of Primary Biliary Cholangitis: A Single Centre Study

Table 2

Distribution of IL12RB2 polymorphisms (rs3790567, rs6679356) in PBC patients and control subjects.

SNPGenotypeCount of alleles/genotypesFisher exact
value
OR
Control () (%)PBC () (%)

rs3790567A/G107/409 (20.7/79.3)186/426 (30.4/69.6)0.000911.51.7 [1.3–2.2]
AA11 (4.2)29 (9.5)0.025.82.3 [1.1–4.8]
AG85 (33)128 (42)0.024.71,5 [1.0–2.1]
GG162 (62.8)149 (48.5)0.000911.30.6 [0.4–0,8]

rs6679356C/T89/427 (17.2/82.8)153/459 (25/75)0.0029.51.6 [1.2–2.1]
CC11 (4.2)22 (7.2)NS2.21,7 [0.8–3.6]
CT67 (26)109 (35.6)0.016.11,6 [1.1–2.3]
TT180 (69.8)175 (57.2)0.035.10,6 [0.4–0.8]