Table 3: Correlations between plasma PLP level in mice and indices of immune responses.
(a)

PLPXASICD4CD8CD4/CD8IL-2IL-4IFN-γSOCS-1T-bet

PLP1.000
XA−0.6181.000
SI0.284−0.4301.000
CD4−0.684−0.182−0.1051.000
CD80.6840.1820.1051.000
CD4/CD8−0.551−0.275−0.1631.000
IL-2−0.767−0.5300.052−0.052−0.0371.000
IL-40.7410.0050.311−0.2361.000
IFN-γ−0.5130.034−0.6660.666−0.552−0.6470.7061.000
SOCS-1−0.8280.940−0.5330.158−0.1580.069−0.337−0.7121.000
T-bet−0.183−0.6300.0100.866−0.8660.919−0.423−0.779−0.217−0.3271.000

(b)

PLPXASIΔCD4ΔCD8ΔCD4/ΔCD8ΔIL-2ΔIL-4ΔIFN-γΔSOCS-1ΔT-bet

PLP1.000
XA−0.6181.000
SI0.284−0.4301.000
ΔCD4−0.9050.235−0.2211.000
ΔCD80.905−0.2350.2211.000
ΔCD4/ΔCD8−0.8450.139−0.2811.000
ΔIL-20.391−0.730−0.300−0.0240.0240.1231.000
ΔIL-40.6700.1460.149−0.9220.922−0.3231.000
ΔIFN-γ0.839−0.1800.399−0.1660.9381.000
ΔSOCS-1−0.287−0.470−0.2560.651−0.6510.7520.732−0.881−0.7581.000
ΔT-bet−0.6740.787−0.8580.478−0.4780.466−0.170−0.236−0.5520.0841.000

The correlations were calculated as Pearson’s correlation coefficient matrix. CD, cluster of differentiation; IFN-γ, interferon gamma; IL-2, interleukin-2; IL-4, interleukin-4; PLP, pyridoxal 5′-phosphate; SOCS-1, suppressor of cytokine signaling 1; T-bet, T-box transcription factor; XA, xanthurenic acid; Δ means the indictor was detected after ConA stimulation.
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