Research Article

Saliva-Derived Host Defense Peptides Histatin1 and LL-37 Increase Secretion of Antimicrobial Skin and Oral Mucosa Chemokine CCL20 in an IL-1α-Independent Manner

Figure 4

Inflammatory cytokine secretion by keratinocyte-fibroblast cocultures after Hst1 and LL-37 exposure. IL-6, CCL2, CXCL1, and CXCL8 secretion after 24 hours, by skin and gingiva keratinocyte-fibroblast cocultures, is shown. Each bar represents the mean ± standard error mean of 4 independent experiments each performed in duplicate. and .